Methods and compositions for identifying and characterizing indi

Details Methods and compositions for identifying and characterizing indi Methods and compositions for identifying and characterizing indi

1992-11-25

1994-06-14

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 71, 436501, 436506, 436507, 930221, C12Q 170, C12Q 100, G01N 33566, G01N 33564

Patent

active

053209400

ABSTRACT:
Diagnostic assays wherein sera from a patient suspected of having an ill defined autoimmune rheumatic disease is reacted with antigens specific to the human immunodeficiency virus (HIV) core proteins (gag protein products p24 or p17) and envelope proteins env (protein products gp41 and gp160). Immunoreactivity is determined by the formation of an antibody-antigen complex as observed in a Western immunoblot assay. The degree of cross reactivity to the 4 individual proteins is determined, and with this information, a specific and more accurate diagnosis of the disease is made. Once a more accurate diagnosis is determined, the clinician may then proceed with prescribing a therapeutic regimen better suited for the specific patient.

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