Process for the preparation of taurocholanic acids

Organic compounds -- part of the class 532-570 series – Organic compounds – Cyclopentanohydrophenanthrene ring system containing

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C07J 7500, C07J 4100

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055655874

ABSTRACT:
A process is described for the preparation of taurocholanic acids of formula (I): ##STR1## in which A completes the 5.beta.-cyclopentaneperhydrophenanthrene structure of a cholanic acid and E is hydrogen or a methyl group, by reacting the corresponding cholanic acid with the chloride of an acid having a tertiary carbon in the alpha-position, and treating the resulting mixed anhydride with taurine.

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patent: 5500421 (1996-03-01), Parenti
patent: 5508453 (1996-04-01), Arosio
J. Falbe, "Methoden der Organischen Chemie . . . ", 1985, Georg Thieme Verlag, Stuttgart, Germany, pp. 635-636 and 978-981. (no translation)

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