Methods of treating pulmonary hypertension

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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514530, 514623, A61K 3119

Patent

active

050286285

ABSTRACT:
The present invention is concerned with methods for the treatment and diagnosis of pulmonary hypertension which comprise the administration of an effective amount of a compound of formula (I) ##STR1## wherein X is hydrogen or methyl;

REFERENCES:
patent: 4306075 (1981-12-01), Aristoff
Grossman, et al., Pulmonary Hypertension, pp. 835-851, Abnormalities of Circulatory Function.
Ellis, et al., Progress in Medicinal Chemistry, vol. 21, pp. 239-279, 6 Antithrombotic Assessment and Clinical Potential of Prostacyclin Analogues.
Whittle, et al., Platelets and Vascular Occlusion, pp. 1219-1225, vol. 72, No. 6, Dec. 1985, Platelet Actions of Stable Carbocyclic Analogues of Prostacyclin.
Long, et al., Prostacyclin and PGE.sub.1 Treatment of Pulmonary Hypertension.sup.1, pp. 773-776, 1987, 136.
Tyle, Pharmaceutical Research, vol. 3, No. 6, 1986, Iontophoretic Devices for Drug Delivery, pp. 318-326.
Whittle, et al., Progress in Medicinal Chemistry, vol. 21, 1984, pp. 237-279, 6 Antithrombotic Assessment and Clinical Potential of Prostacyclin Analogues.
Supplement-Chest, 89, 6, Jun. 1986, 459S, Pulmonary Vascular Disease II, 2:00-3:00 PM.

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