Compositions containing L-carnitine or an acyl L-carnitine in co

Details Compositions containing L-carnitine or an acyl L-carnitine in co Compositions containing L-carnitine or an acyl L-carnitine in co

1996-03-08

1999-01-19

MacMillan, Keith D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514213, 514221, 514323, 514409, 514419, 514423, 514569, A61K 3712, A61K 3744

Patent

active

058614346

ABSTRACT:
Compositions containing (a) L-carnitine, an acyl L-carnitine, or a pharmacologically acceptable salt thereof in combination with (b) an ACE-inhibitor are useful for treating cardiovascular disorders. Orally, parenterally, rectally or transdermally administrable pharmaceutical compositions in unit dosage form contain from about 0.5 to about 2 g of L-carnitine, or an equimolar amount of an acyl L-carnitine or a pharmacologically acceptable salt thereof, and, e.g., from about 5 to about 20 mg of the ACE-inhibitor lisinopril.

REFERENCES:
patent: 4194006 (1980-03-01), Cavazza
patent: 4599232 (1986-07-01), Bertelli
patent: 5025001 (1991-06-01), Loscalzo et al.
patent: 5037851 (1991-08-01), Cavazza
patent: 5043355 (1991-08-01), Cavazza
patent: 5145871 (1992-09-01), Cavazza
patent: 5173508 (1992-12-01), Cavazza
patent: 5192805 (1993-03-01), Cavazza
patent: 5227518 (1993-07-01), Cavazza
patent: 5270472 (1993-12-01), Taglialatela et al.
patent: 5432199 (1995-07-01), Cavazza

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