Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1994-09-06
1996-10-15
Criares, Theodore J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
A61K 31135
Patent
active
055654959
ABSTRACT:
Selegiline, or a pharmaceutically acceptable salt form of selegiline, is administered to mammals commencing at a point in time at which at least 50% of the mammal's life span is completed, with the administration continuing on a periodic but regular basis over the remaining life span of the mammal. The treatment, which shifts the survival curve, is especially useful for dogs.
REFERENCES:
patent: 4564706 (1986-01-01), Escery et al.
patent: 4861800 (1989-08-01), Buyske
patent: 4871550 (1989-10-01), Millman
patent: 4880833 (1989-11-01), Knoll et al.
patent: 4916151 (1990-04-01), Berg et al.
patent: 5192808 (1993-03-01), Ruehl et al.
patent: 5276057 (1994-01-01), Milgram
Milgram, et al., "Maintenance on L-Deprenyl Prolongs Life in Aged Male Rats", Life Sciences, vol. 47, pp. 415-420. (1990).
Knoll, "Extension of Life Span of Rats by Long-Term (-)Deprenyl Treatment", The Mount Sinai Journal Of Medicine, vol. 55, No. 1, Jan. 1988, pp. 67-74.
Knoll, "The Striatal Dopamine Dependency of Life Span in Male Rats, Longevity Study with (-)Deprenyl", Mechanisms Of Aging And Developments, 46 (1988), 237-262.
Knoll, "The Pharmacology of Selective Mao Inhibitors", Monoamine Oxidase Inhibitors-- The State Of The Art, 1981, pp. 45-61.
Knoll, et al., "Long-Lasting, True Aphrodisiac Efffect of (-)Deprenyl in Sexually Sluggish Old Male Rats", Modl Probl. Pharmacopsychiat., vol. 19, pp. 135, 153 (1983).
Kitani, et al., "Chronic Treatment of (-)Deprenyl Prolongs the Life Span of Male Fischer 344 Rats. Further Evidence", Life Sciences, vol. 52, 1993, pp. 281-288.
Knoll, et al., "Striatal Dopamine, Sexual Activity and Lifespan. Longevity of Rats Treated with (-)Deprenyl", Life Sciences, vol. 45, 1989, pp. 527-531.
Milgram, et al., "Maintenance on L-Deprenyl Prolongs Life in Aged Male Rats", Life Sciences, vol. 47, 1990, pp. 416-420.
Ruehl William W.
Stevens David R.
Criares Theodore J.
Deprenyl Animal Health, Inc.
LandOfFree
Method for survival curve shifting in dogs does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for survival curve shifting in dogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for survival curve shifting in dogs will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1246631