Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-02
1999-01-19
Guzo, David
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 536 235, C12P 2102, C12N 1585
Patent
active
058612726
ABSTRACT:
A human C5a receptor polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for identifying antagonists and agonists to such polypeptide. Antagonists and agonists may be used therapeutically to inhibit or stimulate the C5a receptor. Also disclosed are diagnostic methods for detecting mutations in the polynucleotides of the present invention and for detecting levels of the soluble polypeptides in samples derived from a host.
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Nature, vol. 349, pp. 614-617 (Feb. 14, 1991).
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Biochem. J., vol. 288, pp. 911-917 (1992).
Biochemistry, vol. 30, No. 12, pp. 2993-2999 (1991).
Li Yi
Rosen Craig A.
Guzo David
Human Genome Sciences Inc.
Mullins J. G.
Olstein E. M.
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