Novel intermediates useful in the synthesis of optically active

Details Novel intermediates useful in the synthesis of optically active Novel intermediates useful in the synthesis of optically active

1976-03-29

1977-06-07

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602955R, 260299, 260307FA, C07D26306

Patent

active

040283682

ABSTRACT:
Optically and therapeutically active compounds of the formula: ##STR1## wherein R represents a member selected from the group consisting of a straight or branched alkyl group of from one to twenty carbon atoms (C.sub.1 -C.sub.5 being preferred), an ethoxycarbonyl group, a benzyloxycarbonyl group, a phenyl group, an ##STR2## group, wherein R is as defined above and R.sub.3 is a member selected from the group consisting of a hydrogen atom, a methyl group and a phenyl group, and a 2-, 3-, or 4-pyridyl group, or the HX salts thereof, wherein X represents a pharmaceutically acceptable acid addition salt anion, are prepared using optically active m-hydroxy-.alpha.-[(methylamino)methyl]benzyl alcohol (phenylephrine).

REFERENCES:
patent: 3931212 (1976-01-01), Satzinger et al.

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