Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1980-04-15
1981-09-29
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125LH, A61K 3700, C07C10352
Patent
active
042923131
ABSTRACT:
Peptides which inhibit the secretion of gonadotropins by the pituitary gland and inhibit the release of steroids by the gonads. Administration of an effective amount prevents ovulation of female mammalian eggs and/or the release of steroids by the gonads. The peptides have the structure:
REFERENCES:
"Peptides", Structure and Biological Function, Coy et al., Article, pp. 775-779.
Journal of Medicinal Chemistry, 1977, vol. 20, No. 4, pp. 495-500.
Int. J. Peptido Protein Res., vol. 10, 1977, Felix et al., pp. 299-310.
Rivier Jean E. F.
Vale, Jr. Wylie W.
Phillips Delbert R.
The Salk Institute for Biological Studies
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