1-[.beta.(R-thio)phenethyl]imidazoles and derivatives thereof

Details 1-[.beta.(R-thio)phenethyl]imidazoles and derivatives thereof 1-[.beta.(R-thio)phenethyl]imidazoles and derivatives thereof

1976-03-08

1977-10-25

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

542413, 542426, 542427, 548341, C07D23360, A61K 31415

Patent

active

040556522

ABSTRACT:
Novel 1-[.beta.-(R-thio)phenethyl]-imidazoles and the corresponding 1-[.beta.-(R-sulfinyl)phenethyl]imidazoles and 1-[.beta.-(R-sulfonyl)phenethyl]imidazoles wherein R is alkyl, alkenyl, aralkenyl, substituted aralkenyl, alkynyl, cycloalkyl, cycloalkyl alkyl, aralkyl, substituted aralkyl, aryl or substituted aryl; and the antimicrobial acid addition salts thereof, are useful as antifungal, anti-bacterial and anti-protozoal agents.

REFERENCES:
patent: 3658813 (1972-04-01), Godefroi et al.
patent: 3682951 (1972-08-01), Kreider
patent: 3717655 (1973-02-01), Godefroi et al.
patent: 3796704 (1974-03-01), Metzger et al.
Conant et al. The Chemistry of Organic Compounds revised edition p. 264 N. Y., MacMillan, 1939.

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