Condensed pyrrole mercapto compounds having hypotensive and deco

Details Condensed pyrrole mercapto compounds having hypotensive and deco Condensed pyrrole mercapto compounds having hypotensive and deco

1975-12-19

1977-10-25

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424263, 424273R, 424274, A61K 31505

Patent

active

040556476

ABSTRACT:
The present invention relates to condensed pyrrole mercapto compounds, especially to optionally substituted indole or aza-indole mercapto derivatives, which compounds have ophthalmological and hypotensive properties, in particular vasoconstrictor, especially decongestant properties. It further relates to pharmaceutical compositions containing these compounds. An illustrative example is 3-(2-imidazolin-2-ylthio)-indole hydrochloride or hydroiodide.

REFERENCES:
patent: 3377247 (1968-04-01), Ebce
patent: 3586695 (1971-06-01), Wysong et al.
patent: 3954757 (1976-05-01), Arya et al.
Wilson & Griswold-"Textbook of Organic Medical & Pharmaceutical Chemistry", 4th ed., 1962, pp. 390-391.

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