2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenza

Details 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenza 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenza

1984-04-06

1986-06-03

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546133, A61K 31445

Patent

active

045930341

ABSTRACT:
2-Alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides having the formula ##STR1## wherein X is oxygen or sulfur; R.sub.1 is loweralkyl; and R.sub.2 is selected from the group consisting of hydrogen, halo, 4,5-benzo, alkoxy or Am and n is 1 or 2, and the pharmaceutically acceptable acid addition salts thereof having gastrokinetic and anti-emetic activity are disclosed.

REFERENCES:
patent: 3579523 (1971-05-01), Sandberg et al.
patent: 3857848 (1974-12-01), Mauvernay et al.
patent: 4093734 (1978-06-01), Kruger et al.

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