NK-1 receptor antagonists for the treatment of cancer

Details NK-1 receptor antagonists for the treatment of cancer NK-1 receptor antagonists for the treatment of cancer

Filed on

1997-01-17

Date issued

1999-11-23

Examiner

Goldberg, Jerome D.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Having -c-, wherein x is chalcogen, bonded directly to...

Other Related Categories

A61K 3144

Type

Patent

Status

active

Patent number

059901250

Description

ABSTRACT:
The present invention relates to the use of certain NK-1 receptor antagonists (e.g., substance P receptor antagonists) to treat cancer patients, particularly cancer patients afflicted with a small cell lung carcinoma, APUDoma, astrocytoma, neuroendocrine tumor or extrapulmonary small cell carcinoma.

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Snider, et al., Science, 251, pp. 435-437 (1991).
Swain, et al., Biorg. Med. Chem. Lett., 4(18), pp. 2161-2164 (1994).
Villablanca, et al., Circ. Res., 75(6), pp. 1113-1120 (1994).

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