Human ankyrin family protein

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 4352523, 536 231, C12P 2106, C12N 120, C12N 1500, C07H 2102

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059898631

ABSTRACT:
The invention provides a human ankyrin family protein (ANFP) and polynucleotides which identify and encode ANFP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of ANFP.

REFERENCES:
Lambert, S. et al., "From anemia to cerebellar dysfunction. A review of the ankyrin gene family," Euro. J. Biochem., 211:1-6 (1993).
Lux, S. et al., "Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins," Nature, 344:36-42 (1990).
Otsuka, A. et al., "An Ankyrin-related Gene (unc-44) Is Necessary for Proper Axonal Guidance in Caenorhabditis elegans," The Journal of Cell Biology, 129:1081-1092 (1995).
DeMatteis, M. et al., "The role of ankyrin and spectrin in membrane transport and domain formation," Curr. Opin. Cell Biol., 10:542-549 (1998).
Cosentino, M. et al., (Direct Submission), Genbank Sequence Database (Accession 1841966), National Library of Medicine, Bethesda, Maryland, 20894, (GI 1841966).
Otto, E., (Direct Submission), GenBank Sequence Database (Accession 29491), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894, (GI 29491).

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