Human ion transport-like protein

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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536 231, 536 2431, 4353201, 435325, 4352523, 4351723, C07H 2104, C12N 1512, C12N 1563

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059898615

ABSTRACT:
The invention provides a human ion transport-like protein (HITLP) and polynucleotides which identify and encode HITLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HITLP.

REFERENCES:
Strange, K., "Regulation of Solute and Water Balance and Cell Volume in the Central Nervous System," J. Am. Soc. Nephrol., 3:12-27 (1992).
Ring, M., et al., "Expression of Schistocerca gregaria Ion Transport Peptide (ITP) and its Homologue (ITP-L) in a Baculovirus/Insect Cell System," Insect Biochem. Molec. Biol., 28:51-58 (1998).
Meredith, J., et al., "Locust Ion Tranpsort Peptide (ITP): Primary Structure, cDNA and Expression in a Baculovirus System," J. Exp. Biol., 199:1053-1061 (1996) (GI 1244522 & GI 1244524).
Soyez, D., "Occurrence and Diversity of Neuropeptides from the Crustacean Hyperglycemic Hormone Family in Arthropods," Annals New York Academy of Sciences, 814:319-323 (1997).
Meredith, J., et al., (GI 1244522), GenBank Sequence Database (Accession 1244522), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894.
Meredith, J., et al., (GI 1244524), GenBank Sequence Database (Accession 1244524), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 20894.

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