Autoantibodies and their targets in the diagnosis of peripheral

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436506, 436513, 436518, 436536, 436811, 5303875, G01N 3353, G01N 33564, G01N 33563, C07K 1600

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059898291

ABSTRACT:
The present invention relates to methods of diagnosing peripheral neuropathies by determining the titer of autoantibodies directed toward particular nervous system antigens. It also provides for substantially purified preparations of specific antigens, namely neuroprotein-1, histone H3 (neuroprotein-2), .beta.-tubulin (neuroprotein-3), neuroprotein-4, neuroprotein-5, and NP-9 antigen which can be used in such diagnostic methods.

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