Water soluble complex of a poly (vinyl lactam) and chlorothiazid

Details Water soluble complex of a poly (vinyl lactam) and chlorothiazid Water soluble complex of a poly (vinyl lactam) and chlorothiazid

1986-05-02

1987-12-15

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Lymphokine

424 78, 514222, 514225, 514929, 544 13, A61K 3138, C07D28528

Patent

active

047132388

ABSTRACT:
The invention relates to the novel water soluble chlorothiazide in a complexed state which is derived from the reaction between and N-Vinyl actam polymer and chlorothiazide in alkaline media and to the process for the preparation of said complex.

REFERENCES:
patent: 4291015 (1981-09-01), Keith et al.
patent: 4431644 (1984-02-01), Smith et al.
patent: 4559340 (1985-12-01), Neustadt et al.
Merck et al, Merck & Co. Inc., 9th Ed., 1976, Rahway, N.J., U.S.A., p. 277.
Masaki et al, CA, vol. 77, 1972, 77:164547z.
Copes et al, CA, vol. 79, 1973, 79:18562a, p. 439.

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