Trialkylsilyl pyridinium cephalosporin antibiotics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

540225, C07D50138, A61K 31545

Patent

active

048575216

ABSTRACT:
A cephalosporin derivative represented by the formula ##STR1## wherein R is an organic residue known on .beta.-lactam antibiotics and Q is a radical of ##STR2## dotted-line means a possible double bond, R.sub.1 is hydrogen or monovalent substituent, R.sub.2, R.sub.3 and R.sub.4 are mono-valent substituent, respectively,
a salt thereof, a process for the manufacture thereof and a pharmaceutical agent comprising same.

REFERENCES:
patent: 3449338 (1969-06-01), Flynn
patent: 4152432 (1979-05-01), Heymes et al.
patent: 4504777 (1985-03-01), O'Calloghan et al.
patent: 4600772 (1986-07-01), O'Calloghan et al.

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