Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...
Patent
1997-07-11
1999-03-30
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
4352523, 4353201, 536 232, 536 235, C12N 900, C12N 120, C12N 1500, C07H 2104
Patent
active
058887920
ABSTRACT:
The invention provides a human ATP-dependent RNA helicase (ADRH-1) and polynucleotides which identify and encode ADRH-1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ADRH-1.
REFERENCES:
Ripmaster, T.L., et al., "A putative ATP-dependent RNA helicase involved in Saccharomyces cerevisiae ribosome assembly", Proc. Natl. Acad. Sci. USA, 89:11131-11135 (1992).
Chang, T., et al., "Identification of five putative yeast RNA helicase genes", Proc. Natl. Acad. Sci. USA, 87:1571-1575 (1990).
Pause, A., et al., "The HRIGRXXR Region of the Dead Box RNA Helicase Eukaryotic Translation Initiation Factor 4A Is Required for RNA Binding and ATP Hrdrolysis", Molecular and Cellular Biology, 13:6789-6798 (1993).
Drysdale, B., et al., (GI 1262844) GenBank Sequence Database (Accession U46690), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. (GI 1335873).
Wilson, R., et al., "2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans ", Nature, 368:32-38 (1994).
Wilson, R., et al., (GI 1707045) GenBank Sequence Database (Accession U80447), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. (GI 1707046).
Zhang, S, et al., "Nuclear DNA Helicase II Unwinds both DNA and RNA", Biochemistry, 33:3906-3912 (1994).
Bandman Olga
Corley Neil C.
Guegler Karl J.
Shah Purvi
Incyte Pharmaceuticals Inc.
Slobodyomsky Elijobette
Wax Robert A.
LandOfFree
ATP-dependent RNA helicase protein does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with ATP-dependent RNA helicase protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and ATP-dependent RNA helicase protein will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1213822