Intermediates for prostanoic acids

Details Intermediates for prostanoic acids Intermediates for prostanoic acids

1975-04-10

1977-02-08

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2604488R, 260468H, C07C 6974

Patent

active

040071715

ABSTRACT:
15- And/or 16-alkyl derivatives of 9,15-dioxygenated prost-13-enoic, prosta-4,13-dienoic and prosta-5,13-dienoic acid, lower alkyl esters thereof and homologs thereof, as well as a process for preparing these derivatives are disclosed. The compounds possess hypotensive, antihypertensive, bronchospasmolytic, gastric acid secretion inhibiting, abortifacient, estrus synchronizing and ovulation regulating properties. The compounds also inhibit the aggregation of platelets and promote the disaggregation of aggregated platelets. Methods for their use are also disclosed.

REFERENCES:
abraham, Tet. Letters, 451 (1973).

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