Certain aryl substituted pyrrolopyrazines; a new class of GABA b

Details Certain aryl substituted pyrrolopyrazines; a new class of GABA b Certain aryl substituted pyrrolopyrazines; a new class of GABA b

1992-11-12

1994-02-15

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

540578, 544 71, 544115, 544234, 544345, 544336, 544408, 544409, 548408, 549331, 549341, C07D48704, C07D48710, C07D48714, C07D48720

Patent

active

052868605

ABSTRACT:
This invention encompasses compounds of the formula: ##STR1## and pharmaceutically acceptable non-toxic salts thereof wherein: ##STR2## represents: ##STR3## where n is 0, 1, or 2; R.sub.1 and R.sub.2 are hydrogen or straight or branched chain alkyl groups;

REFERENCES:
patent: 3455943 (1969-07-01), Remers et al.
patent: 4435403 (1984-07-01), Braestrup et al.
patent: 4596808 (1986-06-01), Braestrup et al.
patent: 4623649 (1986-11-01), Huth et al.
patent: 4719210 (1988-01-01), Seidelmann et al.
Certified English translation of H. Biere et al., Liebigs Ann. Chem., 1986, pp. 1749-1764.

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