Growth factor preparation of thymocyte cell culture medium its p

Details Growth factor preparation of thymocyte cell culture medium its p Growth factor preparation of thymocyte cell culture medium its p

1996-12-10

1998-07-07

Walsh, Stephen

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Culture medium, per se

435384, 435326, 435352, 435353, 435354, 435355, 4353722, 4353723, 530399, 530351, 530300, 5303871, 436547, C12N 502, C12N 506, C12N 508, C07K 14475

Patent

active

057767785

ABSTRACT:
The present invention relates to a growth factor preparation derived from a mixed lymphocyte culture, and a process for its production. The invention also relates to a cell culture medium containing said growth factor preparation. The invention further relates to a process for culturing plasma cells and producing antibodies by using said cell culture medium.

REFERENCES:
patent: 4613459 (1986-09-01), Cantor et al.
Sredni et al., Induction of B lympohcyte colony growth in vitro by thymus-derived stimulating factor, Eur. J. Immunol., 8:681-685, 1978.
Andersson et al., Clonal growth and maturation to immunoglobulin secretion in vitro of every growth-inducible B lymphocyte, Cell, 10:27-34, Jan. 1977.
Ganong et al., Review of Medical Physiology, Appleton and Lange (Norwalk, CT), p. 483, 1995.
Roitt, I, "The Acquired Immune Response, I-Consequences of Antigen Recognition", Essential Immunology Chpt. 6, 7th ed., 1991, pp. 105-128.
Roitt, I. "The Acquired Immune Response, II Production of Effectors", Essential Immunology, chpt 7, 7th Ed., 1991, pp. 129-151.
Robert E. Hawkins, "Cell selection strategies for making antibodies from variable gene libraries: trapping the memory pool", Eur. J. Immounol., 1992, 22, pp. 867-870.
Borrebaeck et al, "In Vitro Immunization. Effect of Growth and Differentiation Factors on Antigen-Specific . . . ", The Journal of Immunology, May 15, 1986, pp. 3710-3715.
Kwekkeboom et al, "An efficient procedure for the generation of human monoclonal . . . ", Journal of Immunological Methods, 160(1993) pp. 117-127.

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