Synthetic resin matrix system incorporating healing enhancer

Details Synthetic resin matrix system incorporating healing enhancer Synthetic resin matrix system incorporating healing enhancer

1988-05-27

1989-08-15

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424 81, 424446, 424486, 424487, A61L 1500

Patent

active

048573345

ABSTRACT:
An apparatus and method is described for applying epidermal growth factor (EGF) for achieving healing enhancement at a wound site. The human source of epidermal growth factor, designated as hEGF, is applied from the synthetic resin matrix system of this invention, and which comprises a polymer, such as poly(2-hydroxyl ethyl methyl methacrylate), referred to as PHEMA, an organic solvent, such as polyethylene glycol (PEG), and a hydrogen binding plasticizer, such as dimethylsulfoxide (DMSO). The plasticizer regulates the set-up time of the synthetic resin, so that the more plasticizer present, the shorter the set-up time. The dressing, once formed, and having the healing enhancer contained therein, may be sealed within various backing sheets, in order to preserve its aseptic condition. When ready for use, one of the backing sheets may be peeled away to expose the resin pad with the emobodied healing enhancer, ready for application to the wound site.

REFERENCES:
patent: 3287222 (1966-11-01), Larde et al.
patent: 3419006 (1968-12-01), King
patent: 4191743 (1980-03-01), Klemm et al.
patent: 4272518 (1981-06-01), Moro et al.
patent: 4347841 (1982-09-01), Benyo et al.

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