Antibiotic compositions containing validamycin compounds

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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195 80R, 536 17, A61K 3171, C07H 1520

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active

040899470

ABSTRACT:
Novel antibiotics, termed validamycins C, D, E and F, and acid salts thereof, are prepared by cultivating a validamycin-producing strain of microorganism of the genus Streptomyces, and optionally converting the free base to its acid salt. These antibiotics, as well as validoxylamines A and B, are useful for controlling plant diseases, and can be applied to the plants in the form of the cultured broth, filtrate or concentrate thereof, or purified preparation thereof.

REFERENCES:
iwasa et al., "The Journal of Antibiotics", vol. XXIII, No. 12, 1970, pp. 595-602.
Horii et al., "Chem. Abst.", vol. 76, 1972, p. 97891w.

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