Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-08-13
1989-04-25
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31415
Patent
active
048248568
ABSTRACT:
A method of protecting gastrointestinal tract in a mammal from the untoward, non-gastric-acid-induced effects of exposure to gastrointestinally injuruous agents, which comprises administering orally to said mammal a non-antisecretory amount of a benzimidazole derivative having the formula (I): ##STR1## wherein R.sup.1 is the hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a cycloalkyl group, phenyl group or aralkyl group, R.sup.2 is the hydrogen atom or a lower alkyl group, or R.sup.1 and R.sup.2 together with the adjacent nitrogen atom forms a ring, and each of R.sup.3 and R.sup.4 independently is the hydrogen atom, a halogen atom, the trifluoromethyl group, a lower alkyl group, a lower alkoxy group, a lower alkoxycarbonyl group or an amino group.
REFERENCES:
patent: 4359465 (1982-11-01), Ruwart
Hayashi Masatoshi
Nomura Yutaka
Okabe Susumu
Satoh Masaru
Yamakawa Tomio
Ferguson Jr. Gerald J.
Nippon Chemiphar Co., Ltd.
Waddell Frederick E.
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