Pyrazolo[3,4-d]pyrimidine derivatives, their production and use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544262, 544301, A61K 31415, C07D48704

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active

048248487

ABSTRACT:
Novel pyrazolo[3,4-d]pyrimidine derivatives represented by the general formula (I) ##STR1## wherein R.sup.1 is an aryl or heteroaryl group which may be substituted by one to three members selected from the class consisting of halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro, amino, N-C.sub.1-4 alkylamino, N,N-diC.sub.1-4 alkylamino, hydroxy, trifluoromethyl, carbamoyl, N-C.sub.1-4 alkylcarbamoyl and N,N-diC.sub.1-4 alkylcarbamoyl;

REFERENCES:
patent: 3098075 (1963-07-01), Druey
patent: 4603203 (1986-07-01), Furukawa
Central Patents Index, Basic Abstracts Journal, Section B 32972A/18 (Japanese Patent Publication Laid Open No. 31694/1978).
T. Naka et al., Chemical and Pharmaceutical Bulletin 27(6) pp. 1328-1334, 1979.
S. Senda et al., Chemical and Pharmaceutical Bulletin 26(10) pp. 3208-3211, 1978.

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