Process for the preparation of 5-chloromethylpyridines

Details Process for the preparation of 5-chloromethylpyridines Process for the preparation of 5-chloromethylpyridines

1987-08-17

1988-10-18

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546345, 546346, C07D21326

Patent

active

047788968

ABSTRACT:
A process for the preparation of 5-chloromethylpyridines of the formula (I) ##STR1## in which R.sup.1 represents chlorine or nitro,

REFERENCES:
patent: 3123608 (1964-03-01), Mathes et al.
patent: 3931200 (1976-01-01), Gulbenk
patent: 4205175 (1980-05-01), Bowden et al.
J. W. Tilley, P. Levitan and R. W. Kierstead, J. Het. Chem., 16, 333-337, (1979).
H. Fritz, C. D. Weis and T. Winkler, Helv. Chim. Acta, 59, 170-190, (1976).
W. Mathes and H. Schuly, Angew. Chem., 235-240, (1963).
F. E. Ziegler and J. G. Sweeny, J. Org. Chem., 34, 3545-3548, (1969).
Synthesis, Nr. 8, Aug. 1984, Seiten 676-679; G. R. Newkome et al: "Alpha-methyl functionalization of electron-poor heterocycles: free radical chlorination".

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