Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-08-19
1988-10-18
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3144
Patent
active
047788062
ABSTRACT:
A method of inhibiting the production of interleukin-1 by monocytes and/or macrophages in a human in need thereof which comprises administering to such human an effective interleukin-1 production inhibiting amount of a 2-2'-[1,3-propan-2-onediyl-bis(thio)]bis-1H-imidazole or a pharmaceutically acceptable salt thereof.
REFERENCES:
patent: 4188397 (1980-02-01), Hill
Stites, D. P., Stobo, J. D., Fudenberg, H. H., and Wells, J. V., Basic and Clinical Immunology, Lange Medical Publications, Los Altos, Calif., 1984, p. 90.
Ser. No. 856,735, Apr. 28, 1986, Bender et al.
Bender Paul E.
Griswold Don E.
Hanna Nabil
Lee John C.
Canter Carol G.
Friedman Stanley J.
Lentz Edward T.
Lourie Alan D.
SmithKline Beckman Corporation
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