Dihydroquinolinone derivatives, processes for their preparation,

Details Dihydroquinolinone derivatives, processes for their preparation, Dihydroquinolinone derivatives, processes for their preparation,

1986-07-18

1988-10-18

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514312, 5142352, 544128, 544295, 544363, 546128, A61K 31495, C07D40112

Patent

active

047787937

ABSTRACT:
Compounds of the formula I ##STR1## where R(1), R(2), R(3), R(4) and R(5) are, inter alia, hydrogen and alkyl, m is 1-4, n is 0 or 1, p is 0-4 and R(6) is identical or different dialkylamine derivatives, and salts thereof, have a calcium-antagonistic action. They are obtained by reacting corresponding amines with a compound II which carries, on the side chain, a leaving group which can be displaced nucleophilically, or from a hydroxyphenyl-dihydroquinolin-2-one compound by reaction with a corresponding side chain compound which has a leaving group which can be displaced nucleophilically.

REFERENCES:
patent: 3551413 (1970-12-01), Krapcho
patent: 4071520 (1978-01-01), Wehrmeister

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