Esters

Details Esters Esters

1982-09-09

1984-09-11

Torrence, Dolph H.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424305, 560122, 560138, C07C 6914, C07C 6916, A61K 3142

Patent

active

044709978

ABSTRACT:
The invention concerns di- and tri-esters derived from alkanoic, (cycloalkyl)alkanoic, benzoic or phenylalkanoic acids with N-(acylaminoalkyl)-dihydroxyphenylethanolamines, and pharmaceutically acceptable salts thereof; processes for their preparation and manufacture; and pharmaceutical compositions thereof. The esters are useful for the topical treatment of an area of inflammation affecting the skin of a warm-blooded animal. Representative esters of the invention are 1-[3,4-bis(pivaloyloxy)phenyl]-2-[2-(2-phenylacetamido)ethylamino]-ethanol , 1-[3,4-bis(pivaloyloxy)phenyl]-2-[1,1-dimethyl-2-(2-phenoxyacetamido)ethy lamino]-ethanol, and the hydrochlorides and hydrobromides thereof.

REFERENCES:
patent: 3933911 (1976-01-01), Main
patent: 3957870 (1976-05-01), Main

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