Reagent for the early detection of cancer

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435176, 435177, 435180, 424 12, G01N 3354

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active

042885400

ABSTRACT:
A reagent for the early detection of cancer. The reagent is employed in a method comprising the steps of contacting the reagent which consists of bacillus agrobacterium tumefaciens adsorbed on red blood cells, yeast cells or particles selected from the group consisting of polyvinyl latex, kaolin and animal black, with a patient's blood serum and determining whether there a positive reaction of agglutination. The presence of such a reaction indicates that the patient has a cancer in evolution.

REFERENCES:
patent: 3669841 (1972-06-01), Miller
patent: 3953292 (1976-04-01), Burns
patent: 4078971 (1978-03-01), Arkles et al.
AKSAC, S., "Antibody Formation against Agrobacterium tumefaciens in Patients with Various Cancers"; Turk Hij. Tecr. Biyol., Derg. 34 (1-2) pp. 48-51 (1974).
Lippincott, B. B. et al., "Plasmid Content and Tumor Initiation Complementation by Agrobacterium tumefaciens IIBNV6", Jour. of Bact., vol. 132, pp. 824-831 (1977).
Farrand, S. K. et al., Biochemica et Biophysica Acta, 390, pp. 264-275, (1975).

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