Fluorinated nucleosides and process for treating retrovirus infe

Details Fluorinated nucleosides and process for treating retrovirus infe Fluorinated nucleosides and process for treating retrovirus infe

1990-08-13

1992-10-06

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 51, A61K 3170

Patent

active

051531801

ABSTRACT:
A process for treating AIDS, which comprises administering to a patient in need therefor a pharmaceutical composition comprising a therapeutically effective amount of a compound having the formula ##STR1## wherein: R.sub.1 is an adenine, cytosine, guanine, thymidine, uracil, 5-substituted uracil, 5-substituted cytosine derivative, 2-fluoroadenine, 2.6-diaminopurine, 2-aminopurine, 6-thioguanine, or 7-deazaadenine group;

REFERENCES:
patent: 3775397 (1973-11-01), Etzold et al.
patent: 4963662 (1990-10-01), Matthes et al.
The Journal of Biological Chemistry, vol. 262, No. 5, Feb. 15, 1989 pp.2187-2189.

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