Process for producing a para-substituted phenol derivative

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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562508, 568377, 568657, 568813, C07C 6504

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active

045230315

ABSTRACT:
By reacting, using as a catalyst a modified or unmodified cyclodextrin, a phenol compound with an organic halide selected from the group consisting of a carbon tetrahalide and a substituted or unsubstituted allyl halide in the presence of an alkali metal hydroxide, a substituent group derived from said organic halide can be introduced to the para-position of the phenol compound with high selectivity, whereby various useful para-substituted phenol derivatives can be advantageously obtained.

REFERENCES:
Ohara, M. et al., Pharmazie, vol. 33, No. 7, (1978), p. 467.
Chemical Review, 60, 169 (1960).
J. Amer. Chem. Soc., 81, 6446 (1959).
Pharmazie, 33, H, 7 (1978).

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