Method for terminating methadone maintenance through extinction

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514295, 514279, 514289, 514648, A61K 31485, A61K 3144, A61K 31135

Patent

active

055873812

ABSTRACT:
A method is provided for effectively terminating methadone maintenance therapy and the addiction to other legally-available opiates by selectively extinguishing the opiate-taking responses. Selective extinction is produced having sessions in which detoxified addicts make opiate-taking responses while an opiate antagonist blocks the positive reinforcement, interspersed by periods when the antagonist is absent and all responses except opiate-taking can be emitted. A similar method but with instructions not to take the opiate can subsequently be used to protect against resumption of illegal opiate use, or separately with patients addicted to illegal opiates producing reinforcement through the opioidergic system.

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