Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1997-04-25
1998-08-04
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
A61K 31195
Patent
active
057894434
ABSTRACT:
A method for treating flushing as a symptom of menopause is disclosed. Specifically, the method comprises administering to a patient in need thereof an effective amount of leucine, or leucine in combination with isoleucine and valine. Preferably the leucine is administered as a dietary supplement. However, treatment may be achieved via manipulation of dietary protein intake. Due to the depletion effect that leucine has on other branched chain amino acids, it is preferred that isoleucine and valine are administered in combination with leucine.
REFERENCES:
patent: 3608075 (1971-09-01), Glen et al.
patent: 3733407 (1973-05-01), Segre
patent: 4315033 (1982-02-01), Lawrason
patent: 4421744 (1983-12-01), Gormley
patent: 4687781 (1987-08-01), Ehrenpreis et al.
patent: 4730007 (1988-03-01), Ehrenpreis
patent: 4894373 (1990-01-01), Young
patent: 5028622 (1991-07-01), Plaitakis
patent: 5256669 (1993-10-01), Askanazi et al.
patent: 5393784 (1995-02-01), Richardson
DiPalma et al., Annu. Rev. Nutr., "Use of Niacin as a Drug", 11:169-87 (1991).
Carpenter, K.J., Experientia Suppl., "The Relationship of Pellagra to Corn and the Low Availability of Niacin in Cereals", 44:197-222, 1983. (Abstract).
Henderson, Ann. Rev. Nutr., "Niacin", 3:289-307, 1983.
Nutrition Reviews, "Pellagragenic Effect of Excess Leucine", vol. 44, No. 1, Jan. 1986, pp. 26-27.
Nutrition Reviews, "Is Leucine Excess a Factor in Pellagra?", vol. 45, No. 10, Oct. 1987, pp. 313-315.
Harper et al., Ann. Rev. Nutr., "Branched-Chain Amino Acid Metabolism", Ann. Rev. Nutr., pp. 432-439.
Jacob et al., Present Knowledge in Nutrition, "Niacin", pp. 163-169.
Rao et al., Niacin, Niacin, pp. 318-331.
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