Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-02-18
1998-08-04
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C07D22114, C07D40112, C07D22118, A61K 31445
Patent
active
057894183
ABSTRACT:
Disclosed herein are compounds pharmaceutical compositions containing same of the formula
1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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Bousquet, Peter F. et al., "Preclinical Evaluation of LU 79553: A Novel Bis-naphthalimide with Potent Antitumor Activity," Cancer Research 55:1176-1180 (1995).
Berlanga Jose Maria Castellano
Bousquet Peter
Brana Miguel Fernandez
De Vega Maria Jesus Perez
Keilhauer Gerhard
BASF - Aktiengesellschaft
Berch Mark L.
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