Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1998-09-18
1999-10-05
Degen, Nancy
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, 536 243, 536 241, 435375, C07H 2104, C07H 2102
Patent
active
059626712
ABSTRACT:
Antisense compounds, compositions and methods are provided for modulating the expression of FAN. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding FAN. Methods of using these compounds for modulation of FAN expression and for treatment of diseases associated with expression of FAN are provided.
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Adam-Klages et al., Distinct adapter proteins mediate acid versus neutral sphingomyelinase acitvation through the p55 receptor for tumor necrosis factor, J. Leukoc. Biol., 1998, 63:678-682.
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Branch, A., A good antisense molecule is hard to find, TIBS vol. 23, pp. 47-49, Feb. 1998.
Baker Brenda F.
Cowsert Lex M.
Degen Nancy
Epps Janet
Isis Pharmaceuticals , Inc.
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