Use of oligosaccharides for treatment of arthritis

Details Use of oligosaccharides for treatment of arthritis Use of oligosaccharides for treatment of arthritis

1990-12-17

1992-11-17

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

435 18, 436 94, 436501, 436506, 436509, 436827, 536 11, 536 41, 514825, 514885, A61K 3170, A61K 31715

Patent

active

051643740

ABSTRACT:
A method for the treatment of arthritis or a related autoimmune disease that exhibits immune complexes in serum or synovial fluid is provided which comprises exposure of the serum or synovial fluid to an oligosaccharide containing a structural component that inhibits or disrupts the degree of occupancy of the Fc carbohydrate binding site on IgG, e.g., sialyllactose.

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Jaffe, J. Lab. Clin. Med. 60, 409-421 (1962).
Walker Labs. Ltd., Melisa Rheumatoid HAII Immunoassay Kit, Product Insert, 1988.

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