Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-12-16
1999-10-05
Nazario-Gonzalez, Porfirio
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514385, 514415, 514471, 514513, 514542, 560 9, 560 16, 560 17, 560 27, 560 32, 544 63, 544388, 544383, 544319, 544382, 548201, 548230, 548248, 5483311, A01N 4380, A01N 4350, A01N 4338, A01N 4308
Patent
active
059624876
ABSTRACT:
Picornaviral 3C protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of picornaviral 3C proteases. These compounds, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. Several novel methods and intermediates can be used to prepare the novel picornaviral 3C protease inhibitors of the present invention.
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Babine Robert E.
Dragovich Peter S.
Littlefield Ethel S.
Marakovits Joseph T.
Prins Thomas J.
Agouron Pharmaceuticals , Inc.
Davis Brian J.
Nazario-Gonzalez Porfirio
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