Multiple chemically modulated capacitance determination

Details Multiple chemically modulated capacitance determination Multiple chemically modulated capacitance determination

1989-11-17

1992-11-17

Jones, Larry

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

204403, 204400, 435287, C12M 134

Patent

active

051643197

ABSTRACT:
Apparatus and methods are provided for multiple detection of analytes employing semiconductor capacitance as the signal modulated by the analyte. A plurality of semiconductor capacitors are organized for detection (at individual sites) of changes in capacitance which are related to changes in a fluid medium, where the change can be related to the presence of an analyte. Circuitry is designed to substantially maximize sensitivity.

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"Investigation of the Ion Selectivity Mechanism of Hydrogen Ion-Sensitive Field Effect Transistors (ISFET)", Vlasou et al, 3rd Symposium on Ion-Selective Electrodes, pp. 387-397.

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