Human-Th1-specific protein, gene encoding the protein, transform

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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4353201, 530350, 530395, 536 235, C12N 1512, C12N 510

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active

059623195

ABSTRACT:
An element for specifying the condition and type of immune-related diseases on the basis of the knowledge about the polarization of distribution of Th1/Th2 subsets of helper T cells. The element for specifying or correcting the polarization of the Th1/Th2 subsets is implemented by use of a recombinant vector, a transformant, a human-Th1-specific protein, and an antibody which uses the human-Th1-specific protein as an antigen. A human-Th1-specific gene is prepared and specified by a subtraction technique and is incorporated into the recombinant vector. The transformant is formed by transforming the recombinant vector. The Th1-specific protein is encoded by the gene derived from the transformant.

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