Therapeutically effective .omega.-(4-(2-pyridyl)-piperazino)-alk

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D24104, A61K 31495

Patent

active

045101400

ABSTRACT:
The .omega.-[4-(2-pyridyl)-piperazino]-alkanoylanilide compounds having the structural formula (I): ##STR1## wherein n is 1, 2 or 3, each of R, R.sub.1, R.sub.2 R.sub.3, and R.sub.4 is independently hydrogen, halogen, alkyl, alkoxy, OH, NH.sub.2, CF.sub.3, CN, alkylthio, 1-hydroxyalkyl, alkanoyl, NH.sub.2 CO, NH.sub.2 SO.sub.2, alkoxycarbonyl, alkylsulfonyl, benzyloxy, alkanoylamino, NH.sub.2 CONH, 3-phenylureido, 3-alkylureido or alkoxyoxalylamino, R.sub.5 is hydrogen or alkyl, and R.sub.6 is hydrogen or alkoxy, and the pharmaceutically acceptable salts thereof, are effective antianaphylactics, antibronchospastics, antihistaminics, sedatives, analgesics, antiserotonics and blood-pressure-lowering agents.

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