Preparation of radio labeled halogenated compounds

Details Preparation of radio labeled halogenated compounds Preparation of radio labeled halogenated compounds

1988-04-29

1990-12-25

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

548561, C07D22302, C07D20714

Patent

active

049804677

ABSTRACT:
A method for radiolabeling organic compounds is disclosed in which said compounds are contacted with carrier-free radioactive halide ion in the presence of an effective amount of peracetic acid.

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Moerlein et al., "No Carrier-Added Radiobromination and Radioiodination of Aromatic Rings Using In Situ Generated Peracetic Acid," J. Chem. Soc. Perkin Trans., 1 (Apr., 1988).
Abstract of a paper by Kung et al., presented at a conference in San Francisco from Jun. 14-17, 1988 entitled "Preparation of .sup.123 IBZM: A Dopamine Receptor Imaging Agent", pub. May, 1988.
Paper by Kung, Mei-Ping and Kung, Hank F., "Peracetic Acid as a Superior Oxidant for Preparation of .sup.[123] IBZM: A Potential Dopamine D-2 Receptor Imaging Agent," J. of Labeled Compounds and Radiopharmaceuticals, Aug., 1988.

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