Phosphopeptides from casein-based raw material

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues

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530360, 530407, 530832, 424535, A61K 3520, C07K 1506, C07K 1524

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active

049804502

ABSTRACT:
The method consists in subjecting the raw material (milk or retentate) to enzymatic hydrolysis by means of at least one proteolytic enzyme able to reproduce the proteic digestion occuring in vivo in the human body; recovering the thus obtained hydrolyzate; subjecting the latter to at least one ultrafiltration step on membranes able to retaining the phosphopeptides while letting the peptides pass therethrough, the ultrafiltrate thus containing the non phosphorylated peptides; recovering the ultrafiltration retentate; disaggregating the phosphopeptides in the retentate; and subjecting the latter to at least one further ultrafiltration step on membranes which do not retain the phosphopeptides, these being thus separated from the enzyme and available to be recovered as product. The resulting products are useful as dietetic aliments, therapeutic nutriments or medicaments.

REFERENCES:
patent: 3974294 (1976-08-01), Schwille et al.
patent: 4361587 (1982-11-01), Brule et al.
Chem. Abstracts, vol. 66, 1967, 16570j, Schormueller et al., z.
O'Neill et al, cited in Chem. Abstracts, vol. 75:18606k, 1971.
Hiddink et al, cited in Chem. Abstracts, vol. 89:161719u, 1978.

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