Process for producing L-proline by fermentation

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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?, C12P 1324

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044448856

ABSTRACT:
A process for producing L-proline by fermentation, comprising culturing a microorganism belonging to the genus selected from Corynebacterium, Arthrobacter, Brevibacterium, Microbacterium and Saccharomyces and capable of producing L-proline in a culture medium to accumulate L-proline in the cultured liquor and recovering L-proline therefrom, which process is characterized by the use of a culture medium containing at least one member selected from L-glutamic acid and D-, L- and DL-pyrrolidonecarboxylic acid in association with a carbon source, nitrogen source and inorganic compounds.

REFERENCES:
patent: 4224409 (1980-09-01), Nakamori et al.
Kato et al., Applied Microbiology, vol. 23, No. 4, pp. 758-764, Apr. 1972.
Derwent Abstract 62719T of Japanese Pat. No. 38196/1972.
Baich et al., Biochimica et Biophysica Acta, vol. 104, pp. 397-404 (1965).

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