Inhibiting protein interactions

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 721, 435 723, 4351721, 436501, 436518, 436536, 436 63, 436 64, G01N 3353

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active

057363374

ABSTRACT:
Disclosed is a method of evaluating an anti-proliferative compound by contacting the compound with a Raf and determining its ability to bind to Ras, and methods of inhibiting cell proliferation in an animal by administering a compound which reduces the interaction of Ras with Raf.

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