Cuvette for receiving liquid sample

Details Cuvette for receiving liquid sample Cuvette for receiving liquid sample

1989-08-01

1990-12-25

McGraw, Vincent P.

Optics: measuring and testing

Sample, specimen, or standard holder or support

Fluid containers

350618, 350619, 350403, G01N 2103

Patent

active

049798219

ABSTRACT:
A new immunoassay system is provided for the detection of ligands or ligand binding partners in solution in a heterogeneous format. The invention relies upon the detection of back scattered light from an evanescent wave disturbed by the presence of a colloidal gold label brought to the interface by an immunological reaction. The evanescent wave existing at the interface in turn is the result of a totally internally reflected incident light wave. Placement of the detector at a back angle above the critical angle insures a superior signal-to-noise ratio. Apparatus and methods for scanning, detecting and manipulating light including a scattered total internal reflectance immunoassay system are provided.

REFERENCES:
patent: 3939350 (1976-02-01), Kronick et al.
patent: 4181441 (1980-01-01), Noller
patent: 4313734 (1982-02-01), Leuvering
patent: 4521522 (1985-06-01), Lundstrom et al.
Moon, "Biosensors: Chemical Sensing With Light", Sensor Review, Jul. 1988, pp. 121-124.
Edward H. Hellen and Daniel Alexrod, J. Opt. Soc. Am. B., vol. 4 (3): 337-350 (Mar. 1987), Fluorescene Emission at Dielectric and Metal-Film Interfaces.

Affiliated with

Also associated with

Rating

Cuvette for receiving liquid sample does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cuvette for receiving liquid sample, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cuvette for receiving liquid sample will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1159496