Benzoyl-benzoic acid derivatives

Details Benzoyl-benzoic acid derivatives Benzoyl-benzoic acid derivatives

1974-06-07

1976-11-02

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602948G, 2602949, 260295AM, 2603322A, 260465D, 260470, 260473R, 260476R, 260516, 260518R, 260520E, 424263, 424275, 424324, C07C 6520

Patent

active

039897451

ABSTRACT:
The present invention relates to a series of new compounds, their salts and esters and to methods for the preparation of the compounds having the general formula: ##SPC1##
In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; R.sub.2 stands for hydrogen or a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl, alkynyl or alkoxy radical, optionally being substituted with halogen, a lower alkoxy or di-(lower alkyl) amino radical; Ar stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, or lower alkoxy; Y stands for oxygen, sulphur or a methylene radical.
The compounds of the invention which are valuable in the human and veterinary practice, possess a pronounced diuretic and/or saluretic activity.

REFERENCES:
noller, "Chemistry of Organic Compounds", 3rd ed. (1965), p. 259.

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