N-alkyl thiazolidine derivatives

Details N-alkyl thiazolidine derivatives N-alkyl thiazolidine derivatives

1991-07-03

1993-04-13

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548186, 548187, C07D27714, A61K 31425

Patent

active

052023427

ABSTRACT:
This invention relates to the compounds of the formula [I] and salts thereof, which are useful for treatment of liver disorders, ##STR1## wherein X is oxygen or sulfur;

REFERENCES:
patent: 4148800 (1979-04-01), Schubert
Johnston J. Org. Chem. 29, 2442(1964).
Soai, Heterocycles, 22 (12) 2827 (1984).
Yoshimitsu Nagao et al, "Syntheses of rac)3-Substituted 4-Methoxycarbonyl-1,3-thiazolidine-2-thiones via Rearrangement of a Substituted Group from exo-S to N in (rac)2-Substituted Thio-4-methoxycarbonyl-.DELTA..sup.2 -1,3-thiazolines.sup.1,2)", 1988; pp. 495-508, Chem.Pharm.Bull.36(2).
Regina Zibuck et al, "Total Synthesis of (+)-Latrunculin B", 1986, 2451-2453, J. Am.Chem.Soc. 108.

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