Imidazopyridazines

Details Imidazopyridazines Imidazopyridazines

1990-01-31

1993-04-13

Higel, Floyd D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514211, 514212, 514218, 5142222, 5142268, 5142285, 5142288, 5142322, 514254, 540545, 540546, 540553, 540575, 540599, 544 61, 544117, 544236, A61K 3150, A61K 31535, A61K 3155, C07D48704

Patent

active

052023249

ABSTRACT:
The imidazo[1,2-b]pyridazine compounds of the formula: ##STR1## wherein R.sub.1 is a hydrogen or halogen atom, or a lower alkyl group optionally having substituent(s), R.sub.2 and R.sub.3 are, independently, a hydrogen atom, a lower alkyl group optionally having substituent(s), a cycloalkyl group or a phenyl group optionally having substituent(s) or R.sub.2 and R.sub.3 together with the adjacent nitrogen atom to which they bond may form a heterocyclic ring optionally having substituent(s), X is an oxygen atom or S(O).sub.n (n=0 to 2), Alk is a straight or branched chain alkylene group containing 1-10 carbon atoms and optionally having substituent(s), or their pharmaceutically acceptable salts which possess antiallergic, anti-inflammatory and anti-PAF activities, and their production and use.

REFERENCES:
patent: 4330543 (1982-05-01), Baldwin et al.
patent: 4353903 (1982-10-01), Fabiane et al.
patent: 4464372 (1984-08-01), Baldwin et al.
patent: 5145850 (1992-09-01), Miyake et al.
Morrison & Boyd, Organic Chemistry, 5th Ed., Allyn and Bacon, Inc., Boston, (1987) (1959), pp. 702, 703, 953.

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