Labeled antibodies and methods

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

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436531, 436543, 436544, 436545, 436546, 436547, 436815, 436822, 260112R, 260112B, 564284, 564287, 564289, 424 85, 424 88, G01N 3354, G01N 3358

Patent

active

044904738

ABSTRACT:
Sandwich immunoassays are provided wherein an anti-analyte antibody is coupled with a detector labeled antibody, the anti-analyte antibody being substituted with a N,N,N-trimethylammoniumphenyl group and the detector labeled antibody is an antibody specific to the N,N,N-trimethylammoniumphenyl group. The invention includes novel assays, antigens and antibodies.

REFERENCES:
Prange, et al., J. of Immunology, vol. 118, #4, (1977), pp. 1311-1316.
Alevy et al., J. Immunology, vol. 124, #1, (1980), pp. 215-221.
Alevy et al., J. Exp. Med., vol. 151, (1980), pp. 528-541.

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